James R. Falsey;Seifu Tadesse;Andrew Tasker;Fang-Tsao Hong
发明人:
Fang-Tsao Hong,James R. Falsey,Seifu Tadesse,Andrew Tasker
申请号：
US12616646
公开号：
US08247409B2
申请日:
2009.11.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula Iwherein A1, A2, B, R2 and R3 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
