Daniel D. Long,Lan Jiang,Daisuke Roland Saito,Priscilla Van Dyke
申请号：
US12703931
公开号：
US08211894B2
申请日:
2010.02.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides heteroarylene substituted 8-azabicyclo[3.2.1]octane compounds of formula (I):wherein R1, R2, A, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
