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INTRAORAL FILM-LIKE BASE AGENT AND FORMULATION
专利权人:
NITTO DENKO CORPORATION
发明人:
ASARI, DAISUKE,HORI, MITSUHIKO,OGAWA, KEIKO
申请号:
EP09839222
公开号:
EP2399574A4
申请日:
2009.03.06
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a drug. The base is produced by dispersing, in an organic solvent having a solubility parameter of 9.7 or higher, an edible polymer soluble in water and the organic solvent, and particles of one or two or more compounds selected from the group consisting of mono- to hexasaccharide sugars and sugar alcohols thereof which have an average particle size of 0.1 µm to 60 µm and are insoluble in an organic solvent. The present invention can therefore provide oral film-form base and preparation which have a rapid dissolution profile in the mouth and sufficient film strength, and provide a reduced sticky sensation attributed to the water-soluble polymer in the mouth and an improved feel when handled with the fingers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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