THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NA;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
发明人:
SAVARINO, STEPHEN
申请号:
CA2890380
公开号:
CA2890380A1
申请日:
2013.10.08
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The inventive subject matter relates to a recombinant polypeptide construct comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the inductin of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti- enterotoxigenic Escherichia coli.