Recombinant polypeptide construct comprising multiple enterotoxigenic Escherichia coli fimbrial subunits

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专利权人:

Stephen Savarino

发明人:

Stephen Savarino

申请号：

US15079388

公开号：

US20160194362A1

申请日:

2016.03.24

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The inventive subject matter relates to a recombinant polypeptide constructs comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the induction of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti-enterotoxigenic Escherichia coli immunity.

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