The present invention relates to compositions comprising Graptopetalum and uses thereof. Graptopetalum can protect animals from liver diseases and medical conditions, such as inflammation, steatosis, and fibrosis. In particular, Graptopetalum inhibits proliferation of activated hepatic stellate cells, which play a pivotal role in liver fibrosis. Graptopetalum also has anti－fibrosis activities as well as inhibits proliferation of lung fibroblasts. Therefore, in addition to being a prophylactic and therapeutic agent for the liver, Graptopetalum is useful against fibrosis or inflammation of tissues or organs other than the liver, in particular lung, kidney, and bladder. Other plants in the family of Crassulaceae, particularly Echeveria, have similar effects as Graptopetalum.本發明係關於包括風車草屬(Graptopetalum)植物的組成物及其用途。風車草屬植物可保護動物使之對抗到肝臟疾病與例如發炎、脂肪變性、以及纖維樣變性的醫學病症。特別的，風車草屬植物會抑制活化的肝臟星狀細胞之增殖，而該細胞在肝臟纖維樣變性扮演一個重要的角色。風車草屬植物也具有抗－纖維樣變性活性以及會抑制肺臟成纖維細胞之增殖。因此，風車草屬植物除了為一種肝臟的預防與治療作用劑之外，其也有用於對抗肝臟之外的組織或器官(特別是肺臟、腎臟、與膀胱)之纖維樣變性或發炎。其他景天科(Crassulaceae)的植物，特別是擬石蓮花屬(Echeveria)植物，具有與風車草屬植物類似的效果。
