This invention regards the composition and its use which include guraputopetarumu being attached. guraputopetarumu being attached can protect the animal from the liver disease and the condition like the inflammation, the fat symptom, and the tissue symptom. Especially, guraputopetarumu being attached can obstruct the multiplication of the activated liver star cell which possesses central role in the liver tissue symptom. In addition as for guraputopetarumu being attached it possesses anti- tissue symptom activity, obstructs the multiplication of the lung tissue bud cell. guraputopetarumu being attached is useful vis-a-vis the tissue symptom or the inflammation of organization or the internal organs, the especially lung, the kidney, and the bladder other than the liver in reason, in addition to and the remedy medicine being prevention for the liver. The other plant of crassulacean course, especially ekeberia being attached has the effect which is similar to guraputopetarumu being attached.本発明は、グラプトペタルム属を含む組成物およびその使用に関する。グラプトペタルム属は、炎症、脂肪症、および線維症のような肝疾患および病状から動物を保護できる。特に、グラプトペタルム属は、肝線維症において中枢的役割を有する活性化肝星細胞の増殖を阻害できる。グラプトペタルム属はまた抗線維症活性を有し、肺線維芽細胞の増殖を阻害する。故に、肝臓のための予防的および治療的薬剤であることに加えて、グラプトペタルム属は、肝臓以外の組織または臓器、特に肺、腎臓、および膀胱の線維症または炎症に対して有用である。ベンケイソウ科の他の植物、特にエケベリア属はグラプトペタルム属と同様の効果を有する。
