ALDERBORN, GORAN,FORSLUND, ANDERS,HOLMBACK, ULF,LENNERNAS, HANS,GRUDEN, JAN STEFAN PERSSON
申请号：
CA2970991
公开号：
CA2970991A1
申请日:
2015.12.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.
