Orlistat and acarbose modified release composition for the treatment of obesity and related metabolic disorders

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专利权人:

エンプロス ファーマ エービー

发明人:

アルダーボーン，ヨーラン,フォーシュルンド，アンデシュ,ホルムベック，ウルフ,レナーネース，ハンス,グルーデン，ヤーン ステファン パーション

申请号：

JP2017550998

公开号：

JP6607955B2

申请日:

2015.12.17

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.

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