BERTOLOTTI ANNE,DAS INDRAJIT,KRZYZOSIAK AGNIESZKA,ROUSSEAU ADRIEN,SCHNEIDER KIM,SIGURDARDOTTIR ANNA GUDNY
申请号：
IN201737037212
公开号：
IN201737037212A
申请日:
2017.10.20
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to inhibitors of PPP1 R15A and PPP1 R15B and their use in therapy particularly in the treatment of a disease state alleviated by the inhibition of PPP1 R15A and PPP1 R15B for example a disorder associated with accumulation of misfolded proteins or proteostatsis disorder. Compounds of the invention include compounds having the formula IA or a pharmaceutically acceptable salt thereof wherein R R R X and Yare as defined herein.
