Bertolotti, Anne,Das, Indrajit,Krzyzosiak, Agnieszka,Rousseau, Adrien,Schneider, Kim,Sigurdardottir, Anna Gudny
申请号：
AU2016246099
公开号：
AU2016246099A1
申请日:
2016.04.08
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention relates to inhibitors of PPP1 R15A and PPP1 R15B and their use in therapy, particularly in the treatment of a disease state alleviated by the inhibition of PPP1 R15A and PPP1 R15B, for example a disorder associated with accumulation of misfolded proteins or proteostatsis disorder. Compounds of the invention include compounds having the formula IA or a pharmaceutically acceptable salt thereof, wherein R
