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EMBRYONIC ANGIOGENESIS MARKERS AND DIAGNOSTIC AND THERAPEUTIC STRATEGIES BASED THEREON
专利权人:
STICHTING VUMC
发明人:
Arjan Willem GRIFFIOEN,Elisabeth Johanna Maria HUIJBERS,Patrycja NOWAK-SLIWINSKA
申请号:
US16322786
公开号:
US20200017564A1
申请日:
2017.08.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention is in the field of medicine. More specifically, it is in the field of diagnosing tumor angiogenesis status and in the field of medical treatment of a subject who is suffering, suspected to suffer, or might suffer from a tumor in the future. In particular, the invention relates to a fusion polypeptide comprising a foreign antigen and a self antigen, wherein said foreign antigen consists of a polypeptide comprising an amino acid sequence of at least 12-15 amino acid residues, 12-24% of which residues are hydrophilic, bulky amino acid residues selected from the group consisting of histidine, glutamate, arginine, glutamine, aspartic acid and/or lysine.
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