Centre National de la Recherche Scienfitique (CNRS);Centre de Recherches Biologiques et d'Experimentations Cutanees;Institut Europeen de Biologie Cellulaire
发明人:
Michel Hocquaux,Stéphanie Almeida Épouse Scalvino,Elian Lati,Joanna Bakala
申请号:
US15766860
公开号:
US20180291061A1
申请日:
2016.10.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The object of the present invention relates to a novel family of peptide conjugates of formula (I):A-X1-X2-Pro-Ala-X-B (I)wherein: A represents a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue;X1 represents a covalent bond, an alanine or a proline;X2 represents an arginine, a lysine, or an alanine;X represents a lysine, an alanine, or a phenylalanine; andB represents a hydroxyl or an amine;or one of its preferentially pharmaceutically, dermatologically or cosmetically acceptable salts,as well as their synthesis processes and their uses for reducing hair loss and stimulating hair growth.