ROBBINS, STEPHEN MARK,SENGER, DONNA LORRAINE,RAHN, JENNIFER JOY,KUBES, PAUL
申请号:
CA2939266
公开号:
CA2939266A1
申请日:
2015.02.13
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Disclosed are novel peptides comprising SEQ ID NO: 1 and modifications thereof, which are effective in blocking leukocyte recruitment. The disclosed peptides are useful for treating diseases associated with leukocyte recruitment for example inhibiting metastasis of a solid tumor to the liver and lungs and for treating sepsis. Also disclosed are methods of screening for compounds having the ability to block leukocyte recruitment.