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Peptides that Block Leukocyte Recruitment and Methods of Use
专利权人:
INC.;ARCH CANCER THERAPEUTICS
发明人:
STEPHEN MARK ROBBINS,DONNA LORRAINE SENGER,JENNIFER JOY RAHN,PAUL KUBES
申请号:
US16129942
公开号:
US20200038473A1
申请日:
2018.09.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are novel peptides comprising SEQ ID NO: 1 and modifications thereof, which are effective in blocking leukocyte recruitment. The disclosed peptides are useful for treating diseases associated with leukocyte recruitment for example inhibiting metastasis of a solid tumor to the liver and lungs and for treating sepsis. Also disclosed are methods of screening for compounds having the ability to block leukocyte recruitment.
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