ROBBINS, Stephen Mark,SENGER, Donna L.,RAHN, Jennifer Joy,KUBES, Paul
申请号:
EP15749560
公开号:
EP3105245A4
申请日:
2015.02.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed are novel peptides comprising SEQ ID NO: 1 and modifications thereof, which are effective in blocking leukocyte recruitment. The disclosed peptides are useful for treating diseases associated with leukocyte recruitment for example inhibiting metastasis of a solid tumor to the liver and lungs and for treating sepsis. Also disclosed are methods of screening for compounds having the ability to block leukocyte recruitment.