A method and a medication organizer tray apparatus for organizing medications and collecting medication adherence information are provided. The medication organizer tray apparatus includes a support frame, multiple medication bins accommodating multiple medications, a bin cover layer with multiple customized bin labels, and a conductive circuit layer. The support frame includes multiple apertures positioned at predefined intervals from each other for placement of the medication bins. The customized bin labels having medical information printed thereon seal openings of the medication bins. The conductive circuit layer includes conductive lines running along one or more of a lower surface of the bin cover layer, around each medication bin, and a lower surface of each medication bin. The conductive circuit layer electrically communicates with a receptacle base to enable detection of removal of each medication bin from the support frame and detection of tampering of the medication bins.