The invention relates to substituted 3-phenyl-1-(thien-2-yl)propan-1-one derivative compounds of general formula (I)in which: X1 represents a halogen, a R1, -SR1 or -OR1 group X2 represents a sulfur or oxygen atom X3 represents a halogen, a R3, -SR3 or -OR3 group X4 represents a halogen, a R4, -SR4 or –OR4 group X5 represents Y, -S-Y or -O-Y, where Y is a R5-COOR12 or R5-CONR12R13 group X6 represents a halogen, a R6, -SR6 or -OR6 group X7 represents a halogen, a R7, -SR7 or -OR7 group R1 representing a hydrogen or an alkyl group having 1 to 4 carbon atoms, said alkyl group being optionally halogenated by 1-3 halogen atoms R3, R4, R6, R7 and X8 which may be identical or different, selected from hydrogen or an alkyl group having 1 to 4 carbon atoms R5 representing a linear (C1-C4)alkyl group, optionally substituted by 1-2 substituents selected from a (C1-C4)alkyl, (C1-C4)alkenyl or phenyl group A represents: (i) a carbonyl group (CO), (ii) an oxime group (C=N-O-H) or oxime ether group (C=N-O-R11), with R11 selected from a hydrogen atom, an alkyl group (linear or branched) having 1 to 7 carbon atoms, substituted or not with an aryl group, said alkyl and aryl groups being optionally halogenated by 1-3 halogen atoms, or (iii) a-CHORR11 where R11 being selected from a hydrogen atom or alkyl (linear or branched) having 1 to 7 carbon atoms, said alkyl being unsubstituted or substituted with cycloalkyl, aryl or heteroaryl, said alkyl, cycloalkyl, aryl or heteroaryl being optionally halogenated by 1-3 halogen atoms B represents: i) a (CH2-CH2) group, (ii) a (CH-CH) group, n unsubstituted alkene group, having two carbon atoms (CH-CH), their stereoisomers (diastereoisomers, enantiomers), pure or mixed, racemic mixtures, geometric isomers, salts or mixtures thereof where cycloalkyl represents an alkyl group forming one ring with 3-8 carbon atoms aryl represents an aromatic group of 6-14 carbon atoms and representing mono- or bi-cycle heteroaryl represents an aromatic group of 1-
