Philippe Moingeon;Laurence Van Overtvelt;Alain Razafindratsita
发明人:
Philippe Moingeon,Laurence Van Overtvelt,Alain Razafindratsita
申请号:
US11914815
公开号:
US09555102B2
申请日:
2006.05.18
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to an immunogenic composition for sublingual, perlingual or oral administration, comprising at least an antigen and at least an adjuvant that is a bacterium selected from a Bifidobacterium and a lactic acid bacterium, and/or a combination of a corticosteroid with vitamin D3 or any metabolite or analog of the latter, in a pharmaceutically acceptable carrier that is suitable for sublingual, perlingual, or oral administration. Such compositions allow to elicit antigen-specific immune tolerance.