Philippe MOINGEON,Laurence VAN OVERTVELT,Alain RAZAFINDRATSITA
申请号:
US15240628
公开号:
US20170043013A1
申请日:
2016.08.18
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to an immunogenic composition far sublingual, perlingual or oral administration, comprising at least an antigen and at least an adjuvant that is a bacterium selected from a Bifidobacterium and a lactic acid bacterium, and or a combination of a corticosteroid with vitamin D3 or any metabolite or analog of the latter, in a pharmaceutically acceptable carrier that is suitable tor sublingual, perlingual, or oral administration. Such compositions allow to elicit antigen-specific immune tolerance.