present invention, a) a support layer, b) a liner, c) optionally a highly porous membrane, and d) (for i) optionally, an amount of pressure sensitive adhesive up to about 95% by weight of the pharmaceutical composition, (ii) from about 0.1 to 20% by weight of the pharmaceutical composition laquinimod, and (iii) optionally, a pharmaceutical composition comprising one or more penetration enhancers in a total amount of up to about 70% by weight of the pharmaceutical composition including things, to provide a transdermal patch. The present invention comprises administering a transdermal patch as described herein to the skin of a subject, a method for delivering a laquinimod through the skin of a subject, and the human subject is suffering from a form of multiple sclerosis a method of treating also provided. The present invention further provides for use in the treatment of human subjects that suffer from a form of multiple sclerosis, a transdermal patch that is described here.本発明は、a)支持層、b)ライナー、c)任意に高多孔質膜、ならびにd)(i)任意に、医薬組成物の約95重量%までの量の圧感接着剤、(ii)医薬組成物の約0.1~20重量%の量のラキニモド、および(iii)任意に、医薬組成物の約70重量%までの総量の1つ以上の透過促進剤を含む医薬組成物を含む、経皮パッチを提供する。本発明は、対象の皮膚にここで記載される経皮パッチを投与することを含む、対象の皮膚をとおしてラキニモドを送達する方法、および多発性硬化症の一形態に悩んでいるヒト対象を処置する方法も提供する。本発明は、多発性硬化症の一形態に悩んでいるヒト対象の処置において用いるための、ここで記載される経皮パッチをさらに提供する。
