KIM, JUNG MINKR,김정민,LEE, JAE ILKR,이재일,LEE, JUNG MINKR,이정민
申请号:
KR1020130085513
公开号:
KR1020150010882A
申请日:
2013.07.19
申请国别(地区):
KR
年份:
2015
代理人:
摘要:
The present invention relates to a fusion protein having an annexin A2 binding protein, a p53 protein, and a p18 protein bound, and to a pharmaceutical composition including the fusion protein for preventing or treating a cancer. Provided in an embodiment of the present invention is a fusion protein including an annexin A2 binding protein, a p53 protein or a fragment of the same, and a p18 protein. The fusion protein can additionally include one or more selected from the group consisting of an in vitro stabilization protein, a membrane transfer sequence (MTS) domain, a nucleus-cytoplasm signal domain, ATT, and STOPx2.COPYRIGHT KIPO 2015아넥신 A2 결합단백질, p53 단백질 및 p18 단백질이 결합된 융합 단백질, 및 상기 융합 단백질을 포함하는 암의 예방 또는 치료용 약학 조성물에 관한 것이다.