Inhibition of delta-6 desaturase for the treatment of cardiometabolic disease

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专利权人:

发明人:

Adam J. Chicco

申请号：

US13902435

公开号：

US08952012B2

申请日:

2013.05.24

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Systems and methods for screening whether a candidate compound inhibits delta-6 desaturase activity are disclosed. Also disclosed is a transgenic mammal which overexpresses a gene encoding delta-6 desaturase and an animal model of a cardiometabolic disorder or disease that includes the transgenic mammal. A method of treating a cardiometabolic disorder or disease is also disclosed.

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