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Animal model of neurodegenerative disease
专利权人:
Nelson Mandela Metropolitan University
发明人:
Timothy Grant Downing
申请号:
GB201705535
公开号:
GB2561215A
申请日:
2017.04.05
申请国别(地区):
GB
年份:
2018
代理人:
摘要:
An animal (e.g. rat) model of neurodegenerative disease, preferably selected from Alzheimers disease, Parkinsons disease, Lewy body dementia and Amyotrophic lateral sclerosis (ALS), based on the administration of a single dose of beta-N-­methyl amino-L-alanine (BMAA), to induce the neurodegenerative disease. The single dose of BMAA is administered between postnatal day 1 to 6. Also claimed are a non-human animal suitable for use in a method of testing a compound as a treatment of a neurodegenerative disease and a kit comprising BMAA and instruction for its use.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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