INHIBITION OF DELTA-6 DESATURASE FOR THE TREATMENT OF CARDIOMETABOLIC DISEASE

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专利权人:

发明人:

Adam J. Chicco

申请号：

US14592131

公开号：

US20150181845A1

申请日:

2015.01.08

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Systems and methods for screening whether a candidate compound inhibits delta-6 desaturase activity are disclosed. Also disclosed is a transgenic mammal which overexpresses a gene encoding delta-6 desaturase and an animal model of a cardiometabolic disorder or disease that includes the transgenic mammal. A method of treating a cardiometabolic disorder or disease is also disclosed.

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