Provided is a medicine packaging device whereby an ink ribbon can be wound up without slack even without the use of a tension bar. The medicine packaging device includes: a reader-writer 54 that reads information from an IC tag 100 installed at a supply core 31 of an ink ribbon roll detachably installed to an ink ribbon cassette 3 as well as writes information to the IC tag 100; a motor control unit 56 that controls a winding motor for rotating a winding core 32, based on a used length of the ink ribbon which is information read from the IC tag 100, so that the ink ribbon of the ink ribbon roll runs in a winding direction at a higher speed than a feeding speed of a continuous sheet for packaging; and a written information output unit 53 that outputs information showing the used length of the ink ribbon which has been changed due to use of the ink ribbon, to the reader/writer 54 as information written on the IC tag 100.