TREATMENT OF SOLID TUMORS WITH TISSUE INHIBITORS OF METALLOPROTEINASES (TIMPS)
- 专利权人:
- 发明人:
- 申请号:
- EP09777064.8
- 公开号:
- EP2303326B1
- 申请日:
- 2009.07.09
- 申请国别(地区):
- EP
- 年份:
- 2012
- 代理人:
- 摘要:
- The invention belongs to the field of therapies for solid cancers, in particular, skin cancer. Compositions comprising tissue inhibitors of metalloproteinases (TIMPs) linked to anchors for anchoring TIMP into a cell membrane and heatlabile vesicles are provided. Also provided are uses of TIMP or TIMP constructs for treating solid cancers in combination with hyperthermic treatment.
- 来源网站:
- 中国工程科技知识中心
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- Tissue inhibitors of metalloproteinases linked to glycosylphosphatidylinositol (GPI) anchors for the treatment of cancer and skin lesions
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