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Novel lipid tripeptide hydrogelator and hydrogel
专利权人:
日産化学工業株式会社;国立大学法人九州大学
发明人:
宮地 伸英,岩間 武久,後藤 雅宏,丸山 達生,香田 大輔
申请号:
JP2009521682
公开号:
JP5388848B2
申请日:
2008.07.04
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
There is provided a hydrogelator that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A hydrogelator comprising a lipid peptide represented by Formula (1): (where R 1 represents an aliphatic group having 9 to 21 carbon atoms; R 2 , R 3 and R 4 independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s) which may have a branched chain having 1 or 2 carbon atom(s), a phenylmethyl group or a -(CH 2 ) n -X group, and at least one of R 2 , R 3 and R 4 represents a -(CH 2 ) n -X group; n represents the number of 1 to 4; X represents an amino group, a guanidino group, a -CONH 2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which may have 1 to 3 nitrogen atom(s)) or a salt thereof, and a hydrogel comprising the hydrogelator.
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