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Lipid peptide and hydrogel
专利权人:
Nobuhide Miyachi
发明人:
Nobuhide Miyachi,Takehisa Iwama,Masahiro Gotoh,Tatsuo Maruyama,Daisuke Koda
申请号:
US12452473
公开号:
US08916682B2
申请日:
2008.07.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1):(where R1 represents an aliphatic group having 9 to 23 carbon atomsR2, R3, R4 and R5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a —(CH2)n—X group, and at least one of R2, R3, R4 and R5 represents a —(CH2)n—X groupn represents the number of 1 to 4 X represents an amino group, a guanidine group, a —CONH2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s) and in represents 1 or 2), and a hydrogel comprising the lipid peptide.
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