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METHODS FOR STEPWISE DEPOSITION OF SILK FIBROIN COATINGS
专利权人:
TRUSTEES OF TUFTS COLLEGE
发明人:
David L. Kaplan,Xianyan Wang
申请号:
US13775319
公开号:
US20130156844A1
申请日:
2013.02.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides a method for the controlled assembly of layered silk fibroin coatings using aqueous silk fibroin material. The methods described herein can be used to coat substrates of any material, shape, or size. Importantly, the described methods enable control of the biomaterial surface chemistry, thickness, morphology and structure using layered thin film coatings, or bulk coatings. Furthermore, the methods can be performed in all water and do not require intensive chemical processing enabling controlled entrapment of labile molecules such as, drugs, cytokines, and even cells or viruses to generate functional coatings that can be used in a variety of applications.
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