Noorjahan Panjwani;Brian Lawrence;David L. Kaplan;Fiorenzo Omenetto;Jeffrey K. Marchant
发明人:
David L. Kaplan,Fiorenzo Omenetto,Jeffrey K. Marchant,Noorjahan Panjwani,Brian Lawrence
申请号：
US12528634
公开号：
US09102916B2
申请日:
2008.02.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible.
