David L. Kaplan,Fiorenzo G. Omenetto,Jeffrey K. Marchant,Noorjahan Panjwani,Brian Lawrence
申请号：
US15600351
公开号：
US20180036453A1
申请日:
2017.05.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible.
