silk film, fabric engineering construction, methods for preparing a silk film, for covering a surface of a substrate with a silk composition, and for embedding at least one active agent in a silk film, and, film-coated substrate. sedal film
DAVID L. KAPLAN,FIORENZO OMENETTO,SHENZHOU LU,XIAOQIN WANG
申请号：
BRPI0920453
公开号：
BRPI0920453A2
申请日:
2009.10.09
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention provides for compositions and methods for preparing aqueous insoluble, ductile, flexible silk fibroin films. The silk films comprise silk fibroin and about 10% to about 50% (w/w) glycerol, and are prepared by entirely aqueous processes. The ductile silk film may be further treated by extracting the glycerol from and re-drying the silk film. Active agents may be embedded in or deposited on the glycerol modified silk film for a variety of medical applications. The films may be into 3-dimentional structures, or placed on support surfaces as labels or coatings. The glycerol modified silk films of the present invention are useful in variety of applications such as tissue engineering, medical devices or implants, drug delivery, and edible pharmaceutical or food labels.
