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NOUVEAUX DÉRIVÉS D'AMINOPYRIMIDINE COMME INHIBITEURS DE PLK1
专利权人:
MSD K.K.
发明人:
申请号:
EP07851112.8
公开号:
EP2114942B1
申请日:
2007.12.20
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R 1 and R 2 , which may be the same or different, are each a hydrogen atom, a lower alkyl group, a cycloalkyl group, or the like; R 3 and R 4 , which may be the same or different, are each a hydrogen atom, a lower alkyl group, NR a R b , a phenyl group, a lower alkyl group substituted with a phenyl group, a 4- to 7-membered aliphatic heterocyclic group, a lower alkyl group substituted with a 4- to 7-membered aliphatic heterocyclic group, a 5- or 6-membered aromatic heterocyclic group, a lower alkyl group substituted with a 5- or 6-membered aromatic heterocyclic group, or the like; and R 5 is a hydrogen atom, a cyano group, a halogen atom, or a lower alkyl group.
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