Disclosed herein are footwear and systems for reducing foot pain or discomfort. In one aspect, an article of footwear encompasses an upper; a sole, at least one vibration device disposed within the upper, the vibration device comprising at least one vibrational element capable of delivering vibrations to a user of the footwear; a controller communicatively connected to the vibration device and configured to control operation of the one or more vibration devices based on instructions regarding operation of the vibration device; and a control unit communicatively connected to the controller and configured to transmit instructions regarding the operation of the vibration device to the controller. Also disclosed herein are methods for reducing pain and discomfort using the disclosed footwear, devices and systems.