Matthias Kloor,Miriam Reuschenbach,Magnus von Knebel-Doeberitz
申请号:
US15663858
公开号:
US20170340717A1
申请日:
2017.07.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said FSP. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small bowel cancer.