Miriam Reuschenbach;Matthias Kloor;Magnus von Knebel-Doeberitz
发明人:
Matthias Kloor,Miriam Reuschenbach,Magnus von Knebel-Doeberitz
申请号：
US13713753
公开号：
US20140170178A1
申请日:
2012.12.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said FSP. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small bowel cancer.
