Matthias Kloor,Miriam Reuschenbach,Magnus von Knebel-Doeberitz
申请号:
US14926329
公开号:
US09770499B2
申请日:
2015.10.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said FSP. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small bowel cancer.