The University of Tokyo;National University Corporation Tokyo Medical and Dental University
发明人:
申请号:
EP14863728.3
公开号:
EP3072506A4
申请日:
2014.11.21
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides a vesicle, a conjugate, a composition comprising the vesicle or the conjugate, for use in delivering a drug to the brain, and a method for administering the same. The composition of the present invention is a composition for administration to a subject according to a dosing regimen, comprising a carrier for drug delivery, wherein the dosing regimen comprises administering the composition to a subject who has been fasted or caused to have hypoglycemia and inducing an increase in blood glucose level in the subject, and the carrier is modified at the outer surface thereof with a GLUT1 ligand.