Carriers for drug delivery, conjugates, compositions comprising them, and methods for their administration

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专利权人:

国立大学法人;東京大学;国立大学法人 東京医科歯科大学;国立大学法人 東京大学

发明人:

片岡 一則,安楽 泰孝,西山 伸宏,宮田 完二郎,石井 武彦,松本 有,福里 優,溝口 明祐,横田 隆徳,桑原 宏哉,仁科 一隆,水澤 英洋

申请号：

JP2015548997

公开号：

JP6086566B2

申请日:

2014.11.21

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention provides a vesicle, a conjugate, a composition comprising the vesicle or the conjugate, for use in delivering a drug to the brain, and a method for administering the same. The composition of the present invention is a composition for administration to a subject according to a dosing regimen, comprising a carrier for drug delivery, wherein the dosing regimen comprises administering the composition to a subject who has been fasted or caused to have hypoglycemia and inducing an increase in blood glucose level in the subject, and the carrier is modified at the outer surface thereof with a GLUT1 ligand.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/