Process for preparing chiral dipeptidyl peptidase-IV inhibitors

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专利权人:

Merck Sharp & Dohme Corp.;Merck Sharp & Dohme Ltd.

发明人:

Zacuto, Michael, J.,Dunn, Robert, F.,Moment, Aaron, J.,Janey, Jacob, M.,Lieberman, David,Sheen, Faye,Bremeyer, Nadine,Scott, Jeremy,Kuethe, Jeffrey, T.,Tan, Lushi,Chen, Qinghao

申请号：

AU2012275638

公开号：

AU2012275638A1

申请日:

2012.06.25

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.

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