Michael J. Zacuto,Robert F. Dunn,Aaron J. Moment,Jacob M. Janey,David Lieberman,Faye Sheen,Nadine Bremeyer,Jeremy Scott,Jeffrey T. Kuethe,Lushi Tan,Qinghao Chen
申请号:
US14873641
公开号:
US09527855B2
申请日:
2015.10.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A process for the preparation of pyrazolopyrolidines of structural formula I:and W isor P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.