A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT THE PREPARATION THEREOF AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION ALLERGY AND ASTHMA
LEE YONGNAM,YOO JI SEOK,SHIN DAE HEE,RYOO BYUNG HWAN,OH SEI RYANG,AHN KYUNG SEOP,LEE HYEONGKYU,KWON OK KYOUNG,KIM DOO YOUNG,KIM JUNG HEE,SONG HYUK HWAN
申请号：
IN1092/MUMNP/2015
公开号：
IN2015MN01092A
申请日:
2015.05.06
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Pseudolysimachion rotundum subintegrumThe present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of var than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory allergic or asthmatic disease. The purified extract showed more potent anti inflammatory anti allergy and anti asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinolphil the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and golblet cell hyperplasia in a OVA sensitized/challenged mouse model.
