INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY;전남대학교산학협력단;한국해양과학기술원;전남대학교산학협력단;KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY;한국해양과학기술원
发明人:
안긴내,강나래,한의정,신은지,한희진,허수진,김은아,예보람,AHN GIN NAE,KANG NA LAE,HAN EIU JEONG,SHIN EUN JI,HAN HEE JIN,HEO SOO JIN,KIM EUN A,YE BO RAM
申请号:
KR1020180085460
公开号:
KR1020200010866A
申请日:
2018.07.23
申请国别(地区):
KR
年份:
2020
代理人:
摘要:
The present invention inhibits the secretion of β-hexosaminidase from bone marrow derived mast cells (BMMC), inhibits inflammatory cytokine secretion, and NF by including certain compounds or pharmaceutically acceptable salts thereof. It relates to a pharmaceutical composition and health functional food that can exhibit an effect such as inhibiting the expression of -κB factor, and can exhibit excellent efficacy and health functionalities against allergic diseases.본 발명은 특정 화합물 또는 이의 약학적으로 허용되는 염을 포함함으로써, BMMC(bone marrow derived mast cells)의 β-헥소사미니다아제(β-hexosaminidase)의 분비를 억제하고, 염증성 사이토카인 분비 억제, NF-κB인자 발현 억제 등의 효과를 나타내어, 알러지 질환에 대한 우수한 약효 및 건강기능성을 나타낼 수 있는 약학 조성물 및 건강기능식품에 관한 것이다.