PURPOSE: A pharmaceutical composition containing stem cell-derived microvesicles as active ingredients for preventing or treating neurological diseases is provided to obtain a cell therapeutic agent without ethical problems and immunogenicity problems, thereby showing safe treatment effects. CONSTITUTION: A pharmaceutical composition for preventing or treating neurological diseases contains stem cell-derived microvesicles as active ingredients. Stem cells are mesenchymal stem cells which are derived from the brain, liver, lung, umbilical cord blood, fetus blood, kidney, fat tissues, placenta, or bone marrow. The microvesicles have CD13, CD29, CD44, CD73, and CD105 surface antigen-positive property and CD10 and CD90-variable property.본 발명은 줄기세포-유래 미세소포체를 유효성분으로 포함하는 신경질환(neural disease) 예방 또는 치료용 약제학적 조성물에 관한 것이다. 본 발명에 따르면, 본 발명의 조성물은 윤리적 문제 및 면역원성의 문제가 없는 세포치료제를 제공로써, 줄기세포를 직접 이용하는 종래의 방법과 비교하여 보다 안전하고 효과적인 치료 효과를 제공한다.