Leung, Dennis,Nelson, Todd D.,Rhodes, Timothy A.,Kwong, Elizabeth
申请号:
AU2012332894
公开号:
AU2012332894A1
申请日:
2012.10.26
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Described herein is a process for preparing nano-suspensions, wherein the process comprises: providing an admixture of at least one active pharmaceutical compound, an aqueous dispersion medium, and milling media and applying thereto acoustic energy having a frequency of from about 10 hertz to 1000 hertz and which supplies a linear acceleration of from about 10 Gs to about 100 Gs (where "G" is the force of gravity) for a period sufficient to supply a nano-suspension having a D