Abstract A herbal, synergistically acting biscuit was developed by mixing specific amounts of water extract of Spermacoce mohispida seeds, foxtail millet seed flour and palm jaggery in the ratio of 2:65.5:32.5. This mixture significantly lowered the Body Mass Index and fat mass of the High Fat Diet fed animals. The supplementation of this mixture lowered the Total cholesterol, triglyceride, alanine transaminase and aspartate transaminase levels in a synergistic way. It can be used to prevent/treat obesity, Non-alcoholic Fatty Liver Disease and also for healthy body weight control.
