Jinn-Moon Yang,Kai-Cheng Hsu,Tzu-Ying Sung,Shen Rong Lin,Yun-Ming Wang,Kuang-Mei Hsu,Hsin-Ping Lin,Wan-Chun Liu
申请号：
US14599349
公开号：
US09738660B2
申请日:
2015.01.16
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides a compound of formula (I) or the salt thereof:wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or —OR1, and —C(═O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-binding site and a substrate-recognition site of a protein kinase simultaneously. The present invention further provides a pharmaceutical composition, which includes a compound of formula (I) or a salt and a pharmaceutically acceptable carrier thereof. The present invention further provides a use of a compound of formula (I) or a salt thereof, which is for the manufacture of a protein kinase inhibitor as a drug.
