Borje S. ANDERSSON,Benigno C. VALDEZ,Jeffrey TARRAND
申请号：
US16014908
公开号：
US20180296556A1
申请日:
2018.06.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as PEG400 but essentially free of organic solvents and non-solubilized particles. The composition may be further diluted with a desired aqueous diluent such as an infusion fluid for parenteral administration to a subject such as a human. The compositions may be useful for the treatment for diseases or conditions that are sensitive to lipophilic agents, such as infectious diseases, malignant or autoimmune diseases.
