Benigno C. Valdez;Jeffrey Tarrand;Borje S. Andersson
发明人:
Borje S. Andersson,Benigno C. Valdez,Jeffrey Tarrand
申请号：
US15154919
公开号：
US09724345B2
申请日:
2016.05.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as PEG400 but essentially free of organic solvents and non-solubilized particles. The composition may be further diluted with a desired aqueous diluent such as an infusion fluid for parenteral administration to a subject such as a human. The compositions may be useful for the treatment for diseases or conditions that are sensitive to lipophilic agents, such as infectious diseases, malignant or autoimmune diseases.
